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NCLEX Question of the Day
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A patient with a history of chronic kidney disease is prescribed a medication that is primarily excreted by the kidneys. What is the nurse's primary concern regarding the administration of this medication?
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Increased likelihood of allergic reaction.
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Enhanced therapeutic effect.
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Correct answer Risk of medication accumulation and toxicity.
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Faster absorption of the medication.
Rationale
Patients with chronic kidney disease have reduced kidney function, which can lead to decreased excretion of medications that are primarily eliminated by the kidneys. This situation can cause medication accumulation and potentially toxicity. It's crucial to adjust the medication dosage or choose an alternative medication with a different excretion pathway to prevent adverse effects.
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