NCLEX Question of the Day

December 12, 2025

Physiological Adaptation QID 1279

A nurse is evaluating the effectiveness of intravenous mannitol administration for a client with increased intracranial pressure (ICP). Which finding best indicates the medication is achieving its therapeutic goal?

A:
Decreased level of consciousness.
B:
Pupils become fixed and dilated.
C:
Blood pressure decreases to 90/50 mmHg.
D:
Increased urine output.

Explanation

Mannitol is an osmotic diuretic used to reduce increased intracranial pressure. It works by increasing the osmolality of the blood, drawing fluid from the interstitial spaces (including brain tissue) into the intravascular space. This excess fluid is then filtered by the kidneys and excreted as urine. Therefore, a significant increase in urine output (diuresis) is the expected and desired therapeutic effect, indicating that fluid is being effectively removed from the body, which helps to lower ICP.

A decreased level of consciousness or pupils becoming fixed and dilated would indicate worsening ICP, not improvement. Hypotension (BP 90/50 mmHg) can be an adverse effect of mannitol due to excessive fluid removal (dehydration) but is not the desired therapeutic effect related to ICP reduction.

GoodNurse AI

Sign up to access GoodNurse AI, a one-of-a-kind AI tutor who assists you in understanding practice questions better. You can either type in your own question or choose from a list of pre-written questions. GoodNurse AI offers clear explanations and guidance to enhance your learning.

Not subscribed to our free Question of the Day mailing list?