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NCLEX Question of the Day

August 2, 2026 Physiological Adaptation

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Physiological Adaptation QID 1207

A client with a history of Chronic Obstructive Pulmonary Disease (COPD) is admitted with increasing dyspnea and cough. Arterial blood gas (ABG) results show: pH 7.28, PaCO2 65 mmHg, PaO2 55 mmHg, HCO3- 28 mEq/L. How should the nurse interpret these results?

  1. Fully compensated respiratory acidosis

  2. Uncompensated respiratory acidosis

  3. Correct answer Partially compensated respiratory acidosis

  4. Compensated metabolic alkalosis

Rationale

To interpret ABGs: 1. Check pH: 7.28 is acidotic (normal 7.35-7.45). 2. Check PaCO2: 65 mmHg is high (acidic, normal 35-45 mmHg), indicating a respiratory cause. 3. Check HCO3-: 28 mEq/L is high (alkaline, normal 21-28 mEq/L), indicating metabolic compensation. Since the PaCO2 matches the acidosis (respiratory acidosis) and the HCO3- is elevated (attempting to compensate), it is respiratory acidosis with metabolic compensation. Because the pH (7.28) is still outside the normal range (not yet corrected to 7.35-7.45), the compensation is partial. Uncompensated would have a normal HCO3-. Fully compensated would have an abnormal PaCO2 and HCO3- but a normal pH.

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