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NCLEX Question of the Day

August 28, 2026 Pharmacological and Parenteral Therapies

Review the question, check the correct answer, and read the rationale before tomorrow's prompt arrives.

Pharmacological and Parenteral Therapies QID 477

A nurse is preparing to administer eptifibatide to a client with an acute coronary syndrome. Which of the following should the nurse recognize as a contraindication to eptifibatide therapy?

  1. Simultaneous administration of aspirin

  2. Correct answer Active internal bleeding

  3. History of hypertension

  4. Scheduled coronary artery stent placement

Rationale

Eptifibatide is a glycoprotein IIb/IIIa inhibitor that can increase the risk of bleeding. Active internal bleeding is a contraindication for eptifibatide due to the potential for exacerbating the bleeding. While hypertension should be managed, it is not an absolute contraindication. Coronary artery stent placement and simultaneous use of aspirin are part of the typical management of acute coronary syndrome, and eptifibatide can be used in conjunction with these interventions to prevent platelet aggregation and subsequent thrombosis.

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