Endocrine Disorders NCLEX Review: Signs, Symptoms, Pathophysiology & Nursing Management

April 21, 2025

Emily Chang

Endocrine Disorders NCLEX Review: Signs, Symptoms, Pathophysiology & Nursing Management

Are you preparing for the NCLEX exam and feeling overwhelmed by the vast amount of information you need to know? Don’t worry — we’ve got you covered! This article provides a comprehensive review of endocrine disorders, including pathophysiology, signs and symptoms, and nursing management strategies.

By the end of this article, you’ll feel more confident and prepared to tackle any NCLEX questions related to the endocrine system.


Introduction to Endocrine Disorders

The endocrine system plays a vital role in maintaining homeostasis in the body. It consists of glands that produce hormones — chemical messengers that regulate key functions such as metabolism, growth, mood, and reproduction.

When hormone levels become imbalanced, it can lead to a variety of endocrine disorders, many of which are commonly tested on the NCLEX. Understanding these disorders is critical to both safe patient care and exam success.

Want help learning endocrine terms quickly? Check out our 25 Must-Know NCLEX Vocabulary Terms to build your confidence.


Common Endocrine Disorders

1. Diabetes Mellitus

Diabetes mellitus is one of the most commonly tested NCLEX topics and a major cause of chronic illness worldwide.

Pathophysiology:

  • Type 1 Diabetes: Autoimmune destruction of pancreatic beta cells → insulin deficiency.
  • Type 2 Diabetes: Insulin resistance and relative insulin deficiency.

Signs and Symptoms:

  • Polyuria, polydipsia, polyphagia
  • Fatigue, blurred vision, slow wound healing

Nursing Management:

  • Blood glucose monitoring
  • Administering insulin or oral medications
  • Dietary education
  • Foot care and complication prevention

📌 Related: For a med-heavy review, don’t miss our NCLEX Pharmacology Made Easy: Must-Know Drugs


2. Hypothyroidism

Pathophysiology:
Often caused by Hashimoto's thyroiditis, an autoimmune destruction of the thyroid gland.

Signs and Symptoms:

  • Fatigue, weight gain, constipation
  • Cold intolerance, bradycardia, dry skin

Nursing Management:

  • Administering levothyroxine
  • Educating patients on lifelong therapy
  • Monitoring TSH levels

If this topic trips you up, review our NCLEX Categories Explained to see how endocrine disorders fit into the broader exam structure.


3. Hyperthyroidism

Pathophysiology:
Most commonly caused by Graves’ disease, which leads to overstimulation of the thyroid.

Signs and Symptoms:

  • Heat intolerance, weight loss, anxiety
  • Tachycardia, palpitations, insomnia

Nursing Management:

  • Administer antithyroid meds (e.g., methimazole)
  • Monitor for thyroid storm
  • Provide a low-stimulation environment

4. Addison's Disease

Pathophysiology:
Autoimmune destruction of the adrenal cortex, resulting in insufficient cortisol and aldosterone production.

Signs and Symptoms:

  • Fatigue, hypotension, salt craving
  • Hyperpigmentation, electrolyte imbalances

Nursing Management:

  • Corticosteroid and mineralocorticoid replacement
  • Stress-dose steroids for illness or surgery
  • Patient education on adrenal crisis recognition

Need a refresher on symptoms like these? Our article on Vital Organs You Need to Know for the NCLEX might help tie things together.


Conclusion

Endocrine disorders are complex but high-yield on the NCLEX. Understanding their root causes, common signs and symptoms, and nursing interventions is essential for safe clinical practice and exam readiness.

Don’t forget to review:

  • Hormone functions
  • Related lab values (TSH, glucose, cortisol)
  • Common medications and nursing priorities

For more support, explore the resources below and keep reinforcing your knowledge with quizzes, flashcards, and AI tutoring from GoodNurse.com.


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