NCLEX Vocabulary: 20 Essential Nursing Terms to Master with Questions (2025 Guide)

April 7, 2025

Sarah Johnson

NCLEX Vocabulary: 20 Essential Nursing Terms to Master with Questions (2025 Guide)

Preparing for the NCLEX can feel overwhelming, especially with the extensive medical vocabulary involved. To simplify your studies and boost your confidence, we’ve carefully selected 20 essential nursing terms that frequently appear on the NCLEX exam. Master these key terms to enhance your exam readiness and build a strong foundation for your nursing career.

Quick Reference Table

Term Definition Quick NCLEX Tip
Anaphylaxis Severe, life-threatening allergic reaction. Treat immediately with epinephrine.
Bradycardia Heart rate below 60 bpm in adults. Assess patient stability and underlying cause.
Cyanosis Blue/purple skin due to low oxygen. Immediate oxygenation needed.
Diaphoresis Excessive sweating. Common in cardiac emergencies.
Edema Swelling due to fluid retention. Check cardiac, renal, or liver function.
Febrile Relating to fever. Often indicates infection; monitor closely.
Hemostasis Process of stopping bleeding. Essential knowledge for surgical nursing.
Ischemia Reduced blood supply to tissues. Commonly associated with chest pain (angina).
Jaundice Yellow discoloration due to bilirubin. Assess liver function promptly.
Kussmaul Respirations Deep, labored breathing. Indicates severe metabolic acidosis (DKA).
Leukocytosis Elevated white blood cell count. Often signals infection or inflammation.
Malignant Severe, progressive disease (cancer). Understand implications for patient prognosis.
Necrosis Death of tissue due to poor blood flow. Recognize quickly to prevent further damage.
Orthostatic Hypotension Low BP when standing. Teach patient slow positional changes.
Palliative Care Care focused on symptom relief. Integral in chronic and terminal illness care.
Quarantine Isolation to prevent disease spread. Critical for infection control protocols.
Rales Crackling lung sounds. Indicates fluid in lungs (CHF, pneumonia).
Sepsis Life-threatening infection response. Rapid recognition and treatment critical.
Tachypnea Abnormally rapid breathing. Associated with respiratory distress.
Uremia High waste products in blood. Linked to kidney failure; manage carefully.

Why These Terms Matter for the NCLEX in 2025

The NCLEX exam has evolved to emphasize clinical judgment and practical knowledge application. These specific terms are not only common on the exam but integral to scenarios testing your decision-making abilities. Understanding these terms thoroughly will greatly enhance your ability to tackle complex patient scenarios confidently.

Practice Questions

Question 1:

A patient presents to the ER with severe swelling, difficulty breathing, and hives after a bee sting. Which nursing intervention is the priority?

  • A. Administer diphenhydramine
  • B. Administer epinephrine (Correct answer)
  • C. Prepare patient for intubation
  • D. Elevate patient’s legs

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Question 2:

A patient stands quickly and feels dizzy. Blood pressure readings show significant drop upon standing. This condition is known as:

  • A. Bradycardia
  • B. Tachypnea
  • C. Orthostatic hypotension (Correct answer)
  • D. Cyanosis

Question 3:

Deep, labored breathing observed in a diabetic patient with elevated blood glucose is most likely:

  • A. Tachypnea
  • B. Kussmaul respirations (Correct answer)
  • C. Bradypnea
  • D. Eupnea

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Question 4:

A patient with liver dysfunction exhibits yellowing of the skin and eyes. This condition is best documented as:

  • A. Cyanosis
  • B. Necrosis
  • C. Jaundice (Correct answer)
  • D. Diaphoresis

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